{"id":438846,"date":"2025-12-11T11:28:36","date_gmt":"2025-12-11T10:28:36","guid":{"rendered":"https:\/\/www.dynseo.com\/alzheimers-12-modifiable-risk-factors-who\/"},"modified":"2026-01-12T02:04:02","modified_gmt":"2026-01-12T01:04:02","slug":"alzheimers-12-modifiable-risk-factors-who","status":"publish","type":"post","link":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/","title":{"rendered":"Alzheimer&#8217;s: The 12 Modifiable Risk Factors According to the WHO"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Article HTML v8.5&#8243; _builder_version=&#8221;4.16&#8243;][et_pb_row][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243;][et_pb_code admin_label=&#8221;HTML stylis\u00e9&#8221;]<link href=\"https:\/\/fonts.googleapis.com\/css2?family=Montserrat:wght@400;500;600;700;800&#038;display=swap\" rel=\"stylesheet\">\n<style>\n.dynseo-article{font-family:'Montserrat',-apple-system,BlinkMacSystemFont,'Segoe UI',Roboto,sans-serif;line-height:1.8;color:#2c3e50;max-width:100%;box-sizing:border-box}\n.dynseo-article *{box-sizing:border-box}\n.dynseo-article h2{font-size:1.8rem;color:#1a1a2e;margin:50px 0 25px;padding-bottom:12px;border-bottom:3px solid #a9e2e4;font-weight:700}\n.dynseo-article h3{font-size:1.3rem;color:#5e5ed7;margin:35px 0 18px;font-weight:600}\n.dynseo-article h4{font-size:1.1rem;color:#1a1a2e;margin:25px 0 12px;font-weight:600}\n.dynseo-article p{margin-bottom:18px;font-size:1.05rem}\n.dynseo-article a{color:#5e5ed7;text-decoration:none}\n.dynseo-article a:hover{color:#e73469;text-decoration:underline}\n.dynseo-article .dynseo-game-card{display:flex;gap:30px;background:#fff;border-radius:20px;padding:25px;margin:30px 0;border:2px solid #f1f5f9;box-shadow:0 4px 20px rgba(0,0,0,0.06);transition:all .3s}\n.dynseo-article .dynseo-game-card:hover{transform:translateY(-5px);box-shadow:0 15px 40px rgba(0,0,0,0.1);border-color:#a9e2e4}\n.dynseo-article .dynseo-game-card-image{flex:0 0 200px}\n.dynseo-article .dynseo-game-card-image img{width:100%;height:auto;border-radius:16px;box-shadow:0 8px 25px rgba(0,0,0,0.15);transition:transform .3s}\n.dynseo-article .dynseo-game-card-image a:hover img{transform:scale(1.05)}\n.dynseo-article .dynseo-game-card-content{flex:1}\n.dynseo-article .dynseo-game-card-content h4{margin:0 0 15px 0;color:#e73469;font-size:1.3rem}\n.dynseo-article .dynseo-game-card-content h4 a{color:#e73469;text-decoration:none}\n.dynseo-article .dynseo-game-card-content h4 a:hover{color:#5e5ed7}\n.dynseo-article .dynseo-game-card-desc{color:#2c3e50;line-height:1.7}\n.dynseo-article .dynseo-game-card-desc p{margin-bottom:12px}\n.dynseo-article .dynseo-feature-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(250px,1fr));gap:25px;margin:35px 0}\n.dynseo-article .dynseo-feature-card{background:#fff;border-radius:20px;padding:25px;text-align:center;border:2px solid #f1f5f9;transition:all .3s}\n.dynseo-article .dynseo-feature-card:hover{transform:translateY(-8px);box-shadow:0 20px 50px rgba(0,0,0,0.1);border-color:#e73469}\n.dynseo-article .dynseo-feature-card img{max-width:120px;height:auto;margin:0 auto 15px;border-radius:12px;display:block;transition:transform .3s}\n.dynseo-article .dynseo-feature-card a:hover img{transform:scale(1.1)}\n.dynseo-article .dynseo-feature-card h4{color:#1a1a2e;margin:0 0 10px 0;font-size:1.1rem}\n.dynseo-article .dynseo-feature-card h4 a{color:#5e5ed7;text-decoration:none}\n.dynseo-article .dynseo-feature-card h4 a:hover{color:#e73469}\n.dynseo-article .dynseo-feature-card p{color:#64748b;font-size:.95rem;margin:0}\n.dynseo-article .dynseo-figure{margin:30px 0;text-align:center}\n.dynseo-article .dynseo-figure a{display:inline-block;transition:transform .3s}\n.dynseo-article .dynseo-figure a:hover{transform:scale(1.02)}\n.dynseo-article .dynseo-img{max-width:100%;height:auto;border-radius:16px;box-shadow:0 8px 30px rgba(0,0,0,0.12)}\n.dynseo-article img{max-width:100%;height:auto;border-radius:12px;margin:15px 0}\n.dynseo-article .dynseo-button-wrap{margin:25px 0;text-align:center}\n.dynseo-article .dynseo-button{display:inline-block;padding:14px 32px;background:linear-gradient(135deg,#e73469,#db2777);color:white!important;text-decoration:none!important;border-radius:30px;font-weight:600;box-shadow:0 4px 20px rgba(231,52,105,0.35);transition:all .3s}\n.dynseo-article .dynseo-button:hover{transform:translateY(-3px);box-shadow:0 8px 30px rgba(231,52,105,0.45)}\n.dynseo-article .dynseo-cta{background:linear-gradient(135deg,#5e5ed7,#5268c9);border-radius:20px;padding:35px 40px;margin:40px 0;text-align:center;color:white;box-shadow:0 10px 40px rgba(94,94,215,0.3)}\n.dynseo-article .dynseo-cta h3{color:white;font-size:1.5rem;margin:0 0 15px 0}\n.dynseo-article .dynseo-cta p{color:rgba(255,255,255,0.9);margin-bottom:20px}\n.dynseo-article .dynseo-cta .dynseo-button{background:white;color:#5e5ed7!important}\n.dynseo-article .dynseo-intro{font-size:1.15rem;color:#64748b;border-left:4px solid #a9e2e4;padding:20px 25px;margin:35px 0;font-style:italic;background:linear-gradient(90deg,rgba(169,226,228,0.1),transparent);border-radius:0 12px 12px 0}\n.dynseo-article .dynseo-toc{background:linear-gradient(135deg,#f8fafc,#fff);border-radius:20px;padding:35px;margin:40px 0;border:2px solid #e5e7eb;box-shadow:0 4px 20px rgba(0,0,0,0.05)}\n.dynseo-article .dynseo-toc .toc-title{font-size:1.4rem;margin-bottom:25px;color:#1a1a2e;font-weight:700}\n.dynseo-article .dynseo-toc ol{list-style:none;padding:0;margin:0;display:grid;grid-template-columns:repeat(2,1fr);gap:12px}\n.dynseo-article .dynseo-toc li{background:#fff;border-radius:12px;padding:14px 18px;border:2px solid #f1f5f9;transition:all .3s}\n.dynseo-article .dynseo-toc li:hover{transform:translateX(8px);box-shadow:0 6px 20px rgba(0,0,0,0.1)}\n.dynseo-article .dynseo-toc a{color:#1a1a2e;text-decoration:none;font-weight:500}\n.dynseo-article .dynseo-toc a:hover{color:#5e5ed7}\n.dynseo-article .styled-list,.dynseo-article ul{margin:20px 0;padding:0;list-style:none}\n.dynseo-article .styled-list li,.dynseo-article ul li{position:relative;padding-left:28px;margin-bottom:14px}\n.dynseo-article .styled-list li::before,.dynseo-article ul li::before{content:\"\";position:absolute;left:0;top:8px;width:10px;height:10px;background:#e73469;border-radius:50%}\n.dynseo-article blockquote{background:linear-gradient(135deg,#fff9f0,#fff5eb);border-left:4px solid #ffeca7;border-radius:0 16px 16px 0;padding:25px 30px;margin:35px 0}\n.dynseo-article blockquote p{font-style:italic;margin:0}\n.dynseo-article .dynseo-tip-box{background:linear-gradient(135deg,#ecfdf5,#d1fae5);border:2px solid #a9e2e4;border-radius:16px;padding:25px;margin:35px 0}\n.dynseo-article .dynseo-tip-box-title{font-weight:700;color:#1a1a2e;margin-bottom:10px}\n.dynseo-article .dynseo-tip-box-title::before{content:\"\ud83d\udca1 \";font-size:1.2rem}\n.dynseo-article .dynseo-tip-box p{margin:0;color:#2c3e50}\n.dynseo-article .section-divider{text-align:center;margin:60px 0;font-size:1.8rem;letter-spacing:18px;background:linear-gradient(135deg,#ffeca7,#e73469,#a9e2e4);-webkit-background-clip:text;-webkit-text-fill-color:transparent}\n@media(max-width:1024px){.dynseo-article .dynseo-toc{padding:30px}.dynseo-article .dynseo-game-card{gap:20px;padding:20px}.dynseo-article .dynseo-game-card-image{flex:0 0 160px}.dynseo-article .dynseo-cta{padding:30px}}\n@media(max-width:768px){.dynseo-article h2{font-size:1.5rem;margin:40px 0 20px}.dynseo-article h3{font-size:1.15rem;margin:30px 0 15px}.dynseo-article h4{font-size:1rem;margin:20px 0 10px}.dynseo-article p{font-size:1rem;margin-bottom:15px}.dynseo-article .dynseo-toc{padding:25px;margin:30px 0}.dynseo-article .dynseo-toc .toc-title{font-size:1.2rem;margin-bottom:20px}.dynseo-article .dynseo-toc ol{grid-template-columns:1fr;gap:10px}.dynseo-article .dynseo-toc li{padding:12px 15px}.dynseo-article .dynseo-game-card{flex-direction:column;padding:20px;margin:25px 0;gap:20px}.dynseo-article .dynseo-game-card-image{flex:none;text-align:center}.dynseo-article .dynseo-game-card-image img{max-width:180px;margin:0 auto}.dynseo-article .dynseo-game-card-content{text-align:center}.dynseo-article .dynseo-game-card-content h4{font-size:1.15rem}.dynseo-article .dynseo-feature-grid{grid-template-columns:1fr;gap:20px;margin:25px 0}.dynseo-article .dynseo-feature-card{padding:20px}.dynseo-article .dynseo-feature-card img{max-width:100px}.dynseo-article .dynseo-figure{margin:25px 0}.dynseo-article img{margin:12px 0}.dynseo-article .dynseo-button-wrap{margin:20px 0}.dynseo-article .dynseo-button{display:block;text-align:center;padding:14px 25px}.dynseo-article .dynseo-cta{padding:25px 20px;margin:30px 0}.dynseo-article .dynseo-cta h3{font-size:1.3rem}.dynseo-article .dynseo-intro{padding:15px 18px;margin:25px 0;font-size:1rem}.dynseo-article .dynseo-tip-box{padding:20px;margin:25px 0}.dynseo-article blockquote{padding:20px;margin:25px 0}.dynseo-article .section-divider{margin:40px 0;font-size:1.4rem;letter-spacing:12px}}\n@media(max-width:480px){.dynseo-article{font-size:15px;line-height:1.7}.dynseo-article h2{font-size:1.3rem;margin:35px 0 18px;padding-bottom:10px}.dynseo-article h3{font-size:1.1rem}.dynseo-article p{font-size:.95rem}.dynseo-article .dynseo-toc{padding:20px;margin:25px 0}.dynseo-article .dynseo-toc .toc-title{font-size:1.1rem;margin-bottom:15px}.dynseo-article .dynseo-toc li{padding:10px 12px;font-size:.9rem}.dynseo-article .dynseo-game-card{padding:18px;margin:20px 0}.dynseo-article .dynseo-game-card-image img{max-width:150px}.dynseo-article .dynseo-game-card-content h4{font-size:1.05rem}.dynseo-article .dynseo-game-card-desc{font-size:.9rem}.dynseo-article .dynseo-feature-card{padding:18px}.dynseo-article .dynseo-feature-card img{max-width:80px}.dynseo-article .dynseo-feature-card h4{font-size:1rem}.dynseo-article .dynseo-feature-card p{font-size:.85rem}.dynseo-article .dynseo-button{padding:12px 20px;font-size:.95rem}.dynseo-article .dynseo-cta{padding:20px 18px}.dynseo-article .dynseo-cta h3{font-size:1.15rem}.dynseo-article .dynseo-cta p{font-size:.9rem}.dynseo-article .dynseo-intro{padding:12px 15px;font-size:.95rem}.dynseo-article .dynseo-tip-box{padding:18px}.dynseo-article .styled-list li,.dynseo-article ul li{padding-left:22px;margin-bottom:10px;font-size:.95rem}.dynseo-article .styled-list li::before,.dynseo-article ul li::before{width:8px;height:8px;top:7px}}\n<\/style>\n<div class=\"dynseo-article\">\n<div class=\"dynseo-intro\"><pee>title: Alzheimer&#8217;s&#8217;s prevention: 12 modifiable risk factors WHO reduce dementia 40%<\/pee>\n<pee>description: Complete guide 12 modifiable risk factors Alzheimer&#8217;s&#8217;s according WHO Lancet: prevent 40% dementia cases, act on education, hearing, smoking, depression, social isolation, hypertension, obesity, diabetes, alcohol, head trauma, air pollution, physical inactivity and reduce disease risks.<\/pee>\n<pee>keywords: Alzheimer&#8217;s&#8217;s, prevention, risk factors, WHO, Lancet, dementia, modifiable, reduce risk, health<\/pee>\n<pee>[\/META]<\/pee>\n<pee>Alzheimer&#8217;s&#8217;s, prevention, risk factors, WHO, Lancet, dementia, modifiable, health, risk reduction, lifestyle<\/pee>\n<pee>[\/TAGS]<\/pee>\n<pee><em>Reading time: 36 minutes<\/em><\/pee>\n<a href=\"https:\/\/www.dynseo.com\/en\/courses\/alzheimers-understanding-the-disease-and-finding-solutions-for-everyday-life\/\" target=\"_blank\"><a href=\"https:\/\/www.dynseo.com\/en\/wp-content\/uploads\/2025\/11\/Alzheimer-_-compren\u2026-Anglais.jpg\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.dynseo.com\/en\/wp-content\/uploads\/2025\/11\/Alzheimer-_-compren\u2026-Anglais.jpg\" alt=\"DYNSEO Alzheimer's Training\" style=\"max-width:100%;height:auto;\" \/><\/a><\/a>\n<pee>&#8220;Alzheimer&#8217;s&#8217;s is a genetic lottery, nothing can be done.&#8221; &#8220;If it&#8217;s in my genes, I&#8217;ll get it anyway.&#8221; &#8220;Prevention doesn&#8217;t really work.&#8221; &#8220;Too late for me, I&#8217;m 60.&#8221;<\/pee>\n<pee>FALSE. Alzheimer&#8217;s&#8217;s \u2260 Inevitable genetic fate. Science reveals: 40% of dementia cases could be prevented or delayed by acting on 12 modifiable risk factors. That&#8217;s huge. The Lancet Commission (2020, updated 2024), validated by WHO, identifies these factors: Limited education, hearing loss, smoking, depression, social isolation, hypertension, obesity, diabetes, excessive alcohol, head trauma, air pollution, physical inactivity. Some act young (education), others midlife (hypertension), others elderly (isolation). Each factor = Power to act. Modifying lifestyle, today, reduces Alzheimer&#8217;s&#8217;s risk, tomorrow.<\/pee>\n<pee>This guide details the 12 factors, explains mechanisms, and provides concrete actions for each.<\/pee>\n<pee><\/pee><\/div>\n<nav class=\"dynseo-toc\">\n<div class=\"toc-title\">\ud83d\udccb Sommaire<\/div>\n<ol>\n<li style=\"border-left:4px solid #ffeca7\"><a href=\"#section-1\">Table of Contents<\/a><\/li>\n<li style=\"border-left:4px solid #e73469\"><a href=\"#section-2\">Alzheimer&#039;s&#039;s Prevention: The Scientific Revolution {#revolution-scientifique}<\/a><\/li>\n<li style=\"border-left:4px solid #a9e2e4\"><a href=\"#section-3\">The 12 Modifiable Risk Factors {#12-facteurs}<\/a><\/li>\n<li style=\"border-left:4px solid #5e5ed7\"><a href=\"#section-4\">Limited Education (youth) {#education}<\/a><\/li>\n<li style=\"border-left:4px solid #5268c9\"><a href=\"#section-5\">Hearing Loss (midlife) {#audition}<\/a><\/li>\n<li style=\"border-left:4px solid #ffeca7\"><a href=\"#section-6\">Smoking (midlife) {#tabac}<\/a><\/li>\n<li style=\"border-left:4px solid #e73469\"><a href=\"#section-7\">Depression (midlife, elderly) {#depression}<\/a><\/li>\n<li style=\"border-left:4px solid #a9e2e4\"><a href=\"#section-8\">Social Isolation (elderly) {#isolement}<\/a><\/li>\n<li style=\"border-left:4px solid #5e5ed7\"><a href=\"#section-9\">Hypertension (midlife) {#hypertension}<\/a><\/li>\n<li style=\"border-left:4px solid #5268c9\"><a href=\"#section-10\">Obesity (midlife) {#obesite}<\/a><\/li>\n<li style=\"border-left:4px solid #ffeca7\"><a href=\"#section-11\">Diabetes (midlife) {#diabete}<\/a><\/li>\n<li style=\"border-left:4px solid #e73469\"><a href=\"#section-12\">Excessive Alcohol Consumption (midlife) {#alcool}<\/a><\/li>\n<li style=\"border-left:4px solid #a9e2e4\"><a href=\"#section-13\">Head Trauma (lifelong) {#traumatismes}<\/a><\/li>\n<li style=\"border-left:4px solid #5e5ed7\"><a href=\"#section-14\">Air Pollution (lifelong) {#pollution}<\/a><\/li>\n<li style=\"border-left:4px solid #5268c9\"><a href=\"#section-15\">Physical Inactivity (lifelong) {#inactivite}<\/a><\/li>\n<li style=\"border-left:4px solid #ffeca7\"><a href=\"#section-16\">Taking Action: Where to Start? {#agir}<\/a><\/li>\n<li style=\"border-left:4px solid #e73469\"><a href=\"#section-17\">Testimonials<\/a><\/li>\n<li style=\"border-left:4px solid #a9e2e4\"><a href=\"#section-18\">Conclusion: 40% of Power in Your Hands<\/a><\/li>\n<\/ol>\n<\/nav>\n<section class=\"dynseo-section\">\n<h2 id=\"section-1\">Table of Contents<\/h2>\n<pee>1. <a href=\"#revolution-scientifique\" target=\"_blank\">Alzheimer&#8217;s&#8217;s Prevention: The Scientific Revolution<\/a><\/pee>\n<pee>2. <a href=\"#12-facteurs\" target=\"_blank\">The 12 Modifiable Risk Factors<\/a><\/pee>\n<pee>3. <a href=\"#education\" target=\"_blank\">Limited Education (youth)<\/a><\/pee>\n<pee>4. <a href=\"#audition\" target=\"_blank\">Hearing Loss (midlife)<\/a><\/pee>\n<pee>5. <a href=\"#tabac\" target=\"_blank\">Smoking (midlife)<\/a><\/pee>\n<pee>6. <a href=\"#depression\" target=\"_blank\">Depression (midlife, elderly)<\/a><\/pee>\n<pee>7. <a href=\"#isolement\" target=\"_blank\">Social Isolation (elderly)<\/a><\/pee>\n<pee>8. <a href=\"#hypertension\" target=\"_blank\">Hypertension (midlife)<\/a><\/pee>\n<pee>9. <a href=\"#obesite\" target=\"_blank\">Obesity (midlife)<\/a><\/pee>\n<pee>10. <a href=\"#diabete\" target=\"_blank\">Diabetes (midlife)<\/a><\/pee>\n<pee>11. <a href=\"#alcool\" target=\"_blank\">Excessive Alcohol Consumption (midlife)<\/a><\/pee>\n<pee>12. <a href=\"#traumatismes\" target=\"_blank\">Head Trauma (lifelong)<\/a><\/pee>\n<pee>13. <a href=\"#pollution\" target=\"_blank\">Air Pollution (lifelong)<\/a><\/pee>\n<pee>14. <a href=\"#inactivite\" target=\"_blank\">Physical Inactivity (lifelong)<\/a><\/pee>\n<pee>15. <a href=\"#agir\" target=\"_blank\">Taking Action: Where to Start?<\/a><\/pee>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-2\">Alzheimer&#039;s&#039;s Prevention: The Scientific Revolution {#revolution-scientifique}<\/h2>\n<h3>Lancet Commission 2020-2024<\/h3>\n<pee><strong>Global Reference<\/strong>:<\/pee>\n<pee><strong>Lancet<\/strong>: Prestigious medical journal (reference).<\/pee>\n<pee><strong>Commission<\/strong>: 28 international experts (neuroscience, epidemiology, public health).<\/pee>\n<pee><strong>Publication<\/strong>: 2020 (updated 2024).<\/pee>\n<pee><strong>Conclusion<\/strong>:<\/pee>\n<pee><strong>40% of dementia cases<\/strong>: Preventable\/delayable (action on modifiable factors).<\/pee>\n<pee><strong>Remaining 60%<\/strong>: Genetics, age, uncontrollable factors (but 40% = Immense).<\/pee>\n<h3>Why This Is Revolutionary<\/h3>\n<pee><strong>Before<\/strong>:<\/pee>\n<pee><strong>Fatalism<\/strong>: &#8220;Alzheimer&#8217;s&#8217;s = Lottery, nothing to do.&#8221;<\/pee>\n<pee><strong>Focus<\/strong>: Medications (repeated failures).<\/pee>\n<pee><strong>Now<\/strong>:<\/pee>\n<pee><strong>Hope<\/strong>: Prevention possible (individual, collective power).<\/pee>\n<pee><strong>Actions<\/strong>: Concrete, accessible (lifestyle).<\/pee>\n<pee><strong>Public Health<\/strong>: Prevention campaigns (governments, WHO).<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Risk Factors<\/strong>:<\/pee>\n<pee><strong>Brain Damage<\/strong>: Inflammation, oxidative stress, vascular damage.<\/pee>\n<pee><strong>Cognitive Reserve<\/strong>: Reduced (compensation capacity).<\/pee>\n<pee><strong>Accumulation<\/strong>: Cumulative effects (multiple factors = Risk +++).<\/pee>\n<pee><strong>Prevention<\/strong>:<\/pee>\n<pee><strong>Reduces Damage<\/strong>: Brain protected.<\/pee>\n<pee><strong>Increases Reserve<\/strong>: Plasticity, connections (disease compensation).<\/pee>\n<pee><strong>Delays Symptoms<\/strong>: Even with amyloid plaques (brain resists more).<\/pee>\n<a href=\"https:\/\/www.dynseo.com\/en\/brain-games-apps\/scarlett-brain-games-for-seniors\/\" target=\"_blank\"><a href=\"https:\/\/www.dynseo.com\/en\/wp-content\/uploads\/2025\/12\/SCARLETT-1.png\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.dynseo.com\/en\/wp-content\/uploads\/2025\/12\/SCARLETT-1.png\" alt=\"SCARLETT Program\" style=\"max-width:100%;height:auto;\" \/><\/a><\/a>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-3\">The 12 Modifiable Risk Factors {#12-facteurs}<\/h2>\n<h3>Overview<\/h3>\n<pee><strong>By Life Period<\/strong>:<\/pee>\n<pee><strong>Youth (<45 years)<\/strong>:<\/pee>\n<pee>1. Limited education<\/pee>\n<pee><strong>Midlife (45-65 years)<\/strong>:<\/pee>\n<pee>2. Hearing loss<\/pee>\n<pee>3. Smoking<\/pee>\n<pee>4. Depression<\/pee>\n<pee>5. Hypertension<\/pee>\n<pee>6. Obesity<\/pee>\n<pee>7. Diabetes<\/pee>\n<pee>8. Excessive alcohol consumption<\/pee>\n<pee><strong>Later Life (>65 years)<\/strong>:<\/pee>\n<pee>9. Social isolation<\/pee>\n<pee>10. Depression (also)<\/pee>\n<pee><strong>Lifelong<\/strong>:<\/pee>\n<pee>11. Head trauma<\/pee>\n<pee>12. Air pollution<\/pee>\n<pee>13. Physical inactivity (implicit in Commission, added from studies)<\/pee>\n<h3>Relative Contribution<\/h3>\n<pee><strong>Estimates<\/strong> (% attributable risk):<\/pee>\n<pee><strong>Limited education<\/strong>: 7%<\/pee>\n<pee><strong>Hearing loss<\/strong>: 8%<\/pee>\n<pee><strong>Hypertension<\/strong>: 2%<\/pee>\n<pee><strong>Obesity<\/strong>: 1%<\/pee>\n<pee><strong>Smoking<\/strong>: 5%<\/pee>\n<pee><strong>Depression<\/strong>: 4%<\/pee>\n<pee><strong>Physical inactivity<\/strong>: 3%<\/pee>\n<pee><strong>Diabetes<\/strong>: 3%<\/pee>\n<pee><strong>Social isolation<\/strong>: 4%<\/pee>\n<pee><strong>Alcohol<\/strong>: 1%<\/pee>\n<pee><strong>Head trauma<\/strong>: 3%<\/pee>\n<pee><strong>Air pollution<\/strong>: 2%<\/pee>\n<pee><strong>Total<\/strong>: ~40% (rounded).<\/pee>\n<pee><\/pee>\n<\/section>\n<div class=\"section-divider\">\u25c6 \u25c6 \u25c6<\/div>\n<section class=\"dynseo-section\">\n<h2 id=\"section-4\">Limited Education (youth) {#education}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Education<\/strong>:<\/pee>\n<pee><strong>Cognitive Reserve<\/strong>: Building (childhood, adolescence, young adults).<\/pee>\n<pee><strong>Neuronal Connections<\/strong>: Learning creates (density, plasticity).<\/pee>\n<pee><strong>Limited Education<\/strong>:<\/pee>\n<pee><strong>Less than 12 years schooling<\/strong>: Increased risk (vs higher education).<\/pee>\n<pee><strong>Brain<\/strong>: Less reserve (limited Alzheimer&#8217;s&#8217;s compensation).<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Early Intellectual Stimulation<\/strong>:<\/pee>\n<pee><strong>Neurons<\/strong>: Connection multiplication (synapses).<\/pee>\n<pee><strong>Plasticity<\/strong>: Flexible, adaptable brain.<\/pee>\n<pee><strong>Adult<\/strong>: Reserve = Buffer (compensated damage).<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>For Yourself<\/strong>:<\/pee>\n<pee><strong>If limited education<\/strong>: Compensate (continuing education, reading, lifelong learning).<\/pee>\n<pee><strong>Never too late<\/strong>: Cognitive stimulation (adult, senior) effective.<\/pee>\n<pee><strong>For Children, Grandchildren<\/strong>:<\/pee>\n<pee><strong>Encourage studies<\/strong>: Maximum possible (not pressure, but support).<\/pee>\n<pee><strong>Reading<\/strong>: From young age.<\/pee>\n<pee><strong>Cognitive activities<\/strong>: Educational games, music, languages.<\/pee>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-5\">Hearing Loss (midlife) {#audition}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Hearing Loss<\/strong>:<\/pee>\n<pee><strong>Midlife<\/strong>: 45-65 years (often ignored, minimized).<\/pee>\n<pee><strong>Alzheimer&#8217;s&#8217;s Risk<\/strong>: +8% (major factor).<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Reduced Hearing<\/strong>:<\/pee>\n<pee><strong>Isolation<\/strong>: Difficult conversations (social withdrawal).<\/pee>\n<pee><strong>Cognitive Load<\/strong>: Brain compensates (fatigue, diverted resources).<\/pee>\n<pee><strong>Reduced Stimulation<\/strong>: Sensory inputs (under-stimulated brain).<\/pee>\n<pee><strong>Atrophy<\/strong>: Brain auditory zones (degenerate if not stimulated).<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Screening<\/strong>:<\/pee>\n<pee><strong>Regular<\/strong>: Audiogram (50 years, then every 2-3 years).<\/pee>\n<pee><strong>Signs<\/strong>: Asking to repeat, loud TV, group difficulty.<\/pee>\n<pee><strong>Hearing Aids<\/strong>:<\/pee>\n<pee><strong>Hearing Aids<\/strong>: As soon as loss detected (don&#8217;t wait).<\/pee>\n<pee><strong>Reimbursement<\/strong>: Social security, insurance (recent improvement).<\/pee>\n<pee><strong>Early Correction<\/strong>:<\/pee>\n<pee><strong>Effective<\/strong>: Before established isolation (preserves cognition).<\/pee>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-6\">Smoking (midlife) {#tabac}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Smoking<\/strong>:<\/pee>\n<pee><strong>Alzheimer&#8217;s&#8217;s Risk<\/strong>: +5% (also stroke, cancer, cardiovascular disease).<\/pee>\n<pee><strong>Dose-dependent<\/strong>: More smoking, more risk.<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Toxins<\/strong>:<\/pee>\n<pee><strong>Vascular Damage<\/strong>: Brain arteries (micro-strokes, ischemia).<\/pee>\n<pee><strong>Inflammation<\/strong>: Chronic (brain).<\/pee>\n<pee><strong>Oxidative Stress<\/strong>: Free radicals (damaged neurons).<\/pee>\n<pee><strong>Amyloid Accumulation<\/strong>: Promoted (Alzheimer&#8217;s&#8217;s plaques).<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Quit<\/strong>:<\/pee>\n<pee><strong>Never too late<\/strong>: Even at 60, benefits (brain partially recovers).<\/pee>\n<pee><strong>Aids<\/strong>: Nicotine substitutes, medications (Champix), tobacco specialists.<\/pee>\n<pee><strong>Number<\/strong>: 39 89 (Tobacco Information Service).<\/pee>\n<pee><strong>Avoid passive smoking<\/strong>:<\/pee>\n<pee><strong>Exposure<\/strong>: Also harmful (protect yourself).<\/pee>\n<pee><\/pee>\n<\/section>\n<div class=\"section-divider\">\u25c6 \u25c6 \u25c6<\/div>\n<section class=\"dynseo-section\">\n<h2 id=\"section-7\">Depression (midlife, elderly) {#depression}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Depression<\/strong>:<\/pee>\n<pee><strong>Midlife<\/strong>: +4% Alzheimer&#8217;s&#8217;s risk.<\/pee>\n<pee><strong>Elderly<\/strong>: Factor also (but sometimes early Alzheimer&#8217;s&#8217;s symptom, complex).<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Chronic Depression<\/strong>:<\/pee>\n<pee><strong>Hippocampus<\/strong>: Atrophy (memory area).<\/pee>\n<pee><strong>Inflammation<\/strong>: Cerebral (pro-inflammatory cytokines).<\/pee>\n<pee><strong>Cortisol<\/strong>: Elevated (stress hormone, toxic to neurons).<\/pee>\n<pee><strong>Withdrawal<\/strong>: Social, activities (under-stimulation).<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Treat Depression<\/strong>:<\/pee>\n<pee><strong>Consult<\/strong>: Doctor, psychiatrist, psychologist.<\/pee>\n<pee><strong>Therapies<\/strong>: CBT (cognitive-behavioral therapies), antidepressants (if necessary).<\/pee>\n<pee><strong>Don&#8217;t trivialize<\/strong>: &#8220;It&#8217;s age, it&#8217;ll pass&#8221; (no, treat).<\/pee>\n<pee><strong>Prevention<\/strong>:<\/pee>\n<pee><strong>Physical activity<\/strong>: Natural antidepressant (endorphins).<\/pee>\n<pee><strong>Social<\/strong>: Maintain connections (support).<\/pee>\n<pee><strong>Sleep<\/strong>: Regular (7-8h).<\/pee>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-8\">Social Isolation (elderly) {#isolement}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Isolation<\/strong>:<\/pee>\n<pee><strong>Elderly<\/strong>: +4% Alzheimer&#8217;s&#8217;s risk.<\/pee>\n<pee><strong>Vicious Circle<\/strong>: Isolation \u2192 Cognitive decline \u2192 More isolation.<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Social Interactions<\/strong>:<\/pee>\n<pee><strong>Cognitive Stimulation<\/strong>: Conversations, exchanges (engage memory, language, attention).<\/pee>\n<pee><strong>Positive Emotions<\/strong>: Connections (protective).<\/pee>\n<pee><strong>Isolation<\/strong>:<\/pee>\n<pee><strong>Under-stimulation<\/strong>: Brain (atrophy).<\/pee>\n<pee><strong>Depression<\/strong>: Frequent (risk factor also).<\/pee>\n<pee><strong>Sedentary<\/strong>: Often associated (physical inactivity).<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Maintain Connections<\/strong>:<\/pee>\n<pee><strong>Family, Friends<\/strong>: Calls, visits (regular).<\/pee>\n<pee><strong>Associations<\/strong>: Senior clubs, volunteering, cultural activities.<\/pee>\n<pee><strong>New Encounters<\/strong>: Classes, workshops (never &#8220;too old&#8221;).<\/pee>\n<pee><strong>Technology<\/strong>:<\/pee>\n<pee><strong>Video<\/strong>: Video calls (distant family).<\/pee>\n<pee><strong>Social Networks<\/strong>: Adapted for seniors (stay connected).<\/pee>\n<pee><strong>Animals<\/strong>:<\/pee>\n<pee><strong>Companionship<\/strong>: Dog, cat (indirect social connection, walks, routine).<\/pee>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-9\">Hypertension (midlife) {#hypertension}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Hypertension<\/strong>:<\/pee>\n<pee><strong>Midlife<\/strong>: 45-65 years (+2% Alzheimer&#8217;s&#8217;s risk).<\/pee>\n<pee><strong>Elderly<\/strong>: Link less clear (paradox, too low pressure also risk).<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Elevated Blood Pressure<\/strong>:<\/pee>\n<pee><strong>Vascular Damage<\/strong>: Brain (micro-strokes, leukoaraiosis).<\/pee>\n<pee><strong>Blood-Brain Barrier<\/strong>: Permeability (toxins enter brain).<\/pee>\n<pee><strong>Hypoperfusion<\/strong>: Brain areas (oxygen lack).<\/pee>\n<pee><strong>Vascular Dementia<\/strong>: Direct, but also Alzheimer&#8217;s&#8217;s (mixed lesions).<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Control Pressure<\/strong>:<\/pee>\n<pee><strong>Regular Measurement<\/strong>: Home, doctor.<\/pee>\n<pee><strong>Target<\/strong>: <140\/90 mmHg (midlife), adjust according to age.<\/pee>\n<pee><strong>Treatments<\/strong>:<\/pee>\n<pee><strong>Medications<\/strong>: Antihypertensives (if prescribed, take).<\/pee>\n<pee><strong>Lifestyle<\/strong>:<\/pee>\n<ul class=\"styled-list\">\n<li>Reduce salt (home cooking, avoid prepared meals).<\/li>\n<li>Exercise (30 min\/day).<\/li>\n<li>Healthy weight.<\/li>\n<li>No smoking, moderate alcohol.<\/li>\n<\/ul>\n<pee><\/pee>\n<\/section>\n<div class=\"section-divider\">\u25c6 \u25c6 \u25c6<\/div>\n<section class=\"dynseo-section\">\n<h2 id=\"section-10\">Obesity (midlife) {#obesite}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Obesity<\/strong>:<\/pee>\n<pee><strong>Midlife<\/strong>: BMI \u226530 (+1% Alzheimer&#8217;s&#8217;s risk).<\/pee>\n<pee><strong>Interactions<\/strong>: With diabetes, hypertension (cumulative risk).<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Excess Fat<\/strong>:<\/pee>\n<pee><strong>Inflammation<\/strong>: Chronic (pro-inflammatory adipokines).<\/pee>\n<pee><strong>Insulin Resistance<\/strong>: Brain (disturbed glucose metabolism).<\/pee>\n<pee><strong>Vascular Damage<\/strong>: Atherosclerosis (micro-strokes).<\/pee>\n<pee><strong>Hormones<\/strong>: Imbalances (disturb neurons).<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Lose Weight<\/strong>:<\/pee>\n<pee><strong>Goal<\/strong>: BMI <30 (ideal 20-25).<\/pee>\n<pee><strong>Method<\/strong>:<\/pee>\n<ul class=\"styled-list\">\n<li>Balanced diet (see MIND diet later).<\/li>\n<li>Regular exercise (cardio + Strength).<\/li>\n<li>Medical follow-up (dietitian, doctor).<\/li>\n<\/ul>\n<pee><strong>No drastic diets<\/strong>: Yo-yo (ineffective long term).<\/pee>\n<pee><strong>Prevention<\/strong>:<\/pee>\n<pee><strong>Young<\/strong>: Maintain healthy weight (avoid obesity setting in).<\/pee>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-11\">Diabetes (midlife) {#diabete}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Type 2 Diabetes<\/strong>:<\/pee>\n<pee><strong>Midlife<\/strong>: +3% Alzheimer&#8217;s&#8217;s risk.<\/pee>\n<pee><strong>Also<\/strong>: Vascular dementia.<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Hyperglycemia<\/strong>:<\/pee>\n<pee><strong>Vascular Damage<\/strong>: Micro-angiopathy (brain).<\/pee>\n<pee><strong>Glycation<\/strong>: Proteins (damaged neurons).<\/pee>\n<pee><strong>Cerebral Insulin Resistance<\/strong>: Glucose enters poorly (reduced neuron energy).<\/pee>\n<pee><strong>Inflammation<\/strong>: Chronic.<\/pee>\n<pee><strong>Alzheimer&#8217;s&#8217;s = &#8220;Type 3 Diabetes&#8221;<\/strong>: Hypothesis (brain insulin resistance).<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Prevent Diabetes<\/strong>:<\/pee>\n<pee><strong>Diet<\/strong>: Low glycemic index, fiber.<\/pee>\n<pee><strong>Exercise<\/strong>: Regular (insulin sensitivity).<\/pee>\n<pee><strong>Weight<\/strong>: Maintain health.<\/pee>\n<pee><strong>If Diabetes<\/strong>:<\/pee>\n<pee><strong>Control Blood Sugar<\/strong>: HbA1c <7% (target).<\/pee>\n<pee><strong>Treatments<\/strong>: Antidiabetics (take correctly).<\/pee>\n<pee><strong>Follow-up<\/strong>: Medical (vascular complications).<\/pee>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-12\">Excessive Alcohol Consumption (midlife) {#alcool}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Alcohol<\/strong>:<\/pee>\n<pee><strong>Excessive<\/strong>: >21 drinks\/week (+1% Alzheimer&#8217;s&#8217;s risk).<\/pee>\n<pee><strong>Moderate<\/strong>: Debate (some say protective, others neutral).<\/pee>\n<pee><strong>Excessive<\/strong>: Direct brain toxicity.<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Excessive Alcohol<\/strong>:<\/pee>\n<pee><strong>Neurotoxic<\/strong>: Direct (destroys neurons).<\/pee>\n<pee><strong>B1 Deficiency<\/strong>: Thiamine (Wernicke-Korsakoff syndrome, dementia).<\/pee>\n<pee><strong>Vascular Damage<\/strong>: Stroke, brain atrophy.<\/pee>\n<pee><strong>Inflammation<\/strong>: Chronic.<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Limit<\/strong>:<\/pee>\n<pee><strong>Recommendations<\/strong>: Max 10 drinks\/week, 2 drinks\/day, alcohol-free days.<\/pee>\n<pee><strong>Ideal<\/strong>: Less (or zero).<\/pee>\n<pee><strong>If Dependence<\/strong>:<\/pee>\n<pee><strong>Help<\/strong>: Addiction specialists, AA (Alcoholics Anonymous).<\/pee>\n<pee><strong>Withdrawal<\/strong>: Medical (dangerous alone if severe dependence).<\/pee>\n<pee><\/pee>\n<\/section>\n<div class=\"section-divider\">\u25c6 \u25c6 \u25c6<\/div>\n<section class=\"dynseo-section\">\n<h2 id=\"section-13\">Head Trauma (lifelong) {#traumatismes}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Trauma<\/strong>:<\/pee>\n<pee><strong>Repeated mild<\/strong>: Concussions (contact sports, falls).<\/pee>\n<pee><strong>Severe<\/strong>: Accidents (car, serious fall).<\/pee>\n<pee><strong>Alzheimer&#8217;s&#8217;s Risk<\/strong>: +3% (cumulative).<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Impact<\/strong>:<\/pee>\n<pee><strong>Axonal Damage<\/strong>: Neuron connections (damaged).<\/pee>\n<pee><strong>Inflammation<\/strong>: Acute then chronic (if repeated).<\/pee>\n<pee><strong>Tau Accumulation<\/strong>: Protein (tangles, Alzheimer&#8217;s&#8217;s).<\/pee>\n<pee><strong>CTE<\/strong>: Chronic traumatic encephalopathy (boxers, American footballers, early dementia).<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Prevent<\/strong>:<\/pee>\n<pee><strong>Sports<\/strong>: Helmets (cycling, skiing), protections (contact sports).<\/pee>\n<pee><strong>Car<\/strong>: Seatbelt, careful driving.<\/pee>\n<pee><strong>Home<\/strong>: Prevent falls (seniors: stairs, rugs).<\/pee>\n<pee><strong>If Trauma<\/strong>:<\/pee>\n<pee><strong>Rest<\/strong>: Cognitive (limited screens, reading).<\/pee>\n<pee><strong>Consultation<\/strong>: Doctor (monitoring).<\/pee>\n<pee><strong>Don&#8217;t minimize<\/strong>: &#8220;Simple bump&#8221; (if symptoms: headaches, dizziness, confusion).<\/pee>\n<a href=\"https:\/\/www.dynseo.com\/en\/using-scarlett-to-help-people-suffering-from-alzheimers-disease\/\" target=\"_blank\"><a href=\"https:\/\/www.dynseo.com\/en\/wp-content\/uploads\/2022\/01\/Accompagner-les-personnes-Alzheimer.jpg\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.dynseo.com\/en\/wp-content\/uploads\/2022\/01\/Accompagner-les-personnes-Alzheimer.jpg\" alt=\"Free Alzheimer's Guide\" style=\"max-width:100%;height:auto;\" \/><\/a><\/a>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-14\">Air Pollution (lifelong) {#pollution}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Pollution<\/strong>:<\/pee>\n<pee><strong>Fine Particles<\/strong>: PM2.5, PM10 (vehicles, industries).<\/pee>\n<pee><strong>Alzheimer&#8217;s&#8217;s Risk<\/strong>: +2% (chronic exposure).<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Particles<\/strong>:<\/pee>\n<pee><strong>Inhaled<\/strong>: Lungs, then blood (cross blood-brain barrier).<\/pee>\n<pee><strong>Inflammation<\/strong>: Brain (activated microglia).<\/pee>\n<pee><strong>Oxidative Stress<\/strong>: Free radicals.<\/pee>\n<pee><strong>Amyloid Accumulation<\/strong>: Promoted.<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Reduce Exposure<\/strong>:<\/pee>\n<pee><strong>Avoid<\/strong>: Pollution peaks (stay indoors, alert days).<\/pee>\n<pee><strong>Transportation<\/strong>: Less car (walking, cycling quiet routes, public transit).<\/pee>\n<pee><strong>Home<\/strong>: Ventilate (early morning, late evening, avoid rush hours).<\/pee>\n<pee><strong>Air Purifiers<\/strong>: If highly polluted area (HEPA filters).<\/pee>\n<pee><strong>Plants<\/strong>: Indoor (absorb pollutants, modest).<\/pee>\n<pee><strong>Policy<\/strong>:<\/pee>\n<pee><strong>Support<\/strong>: Anti-pollution measures (vote, petitions).<\/pee>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-15\">Physical Inactivity (lifelong) {#inactivite}<\/h2>\n<h3>Impact<\/h3>\n<pee><strong>Sedentary<\/strong>:<\/pee>\n<pee><strong>Alzheimer&#8217;s&#8217;s Risk<\/strong>: +3% (varying estimates).<\/pee>\n<pee><strong>Multifactorial<\/strong>: Links obesity, diabetes, hypertension (factors).<\/pee>\n<h3>Mechanism<\/h3>\n<pee><strong>Physical Exercise<\/strong>:<\/pee>\n<pee><strong>Blood Circulation<\/strong>: Brain (oxygen, nutrients).<\/pee>\n<pee><strong>BDNF<\/strong>: Neurotrophic factor (neuron growth, plasticity).<\/pee>\n<pee><strong>Neurogenesis<\/strong>: Hippocampus (new neurons, even adults).<\/pee>\n<pee><strong>Inflammation<\/strong>: Reduced.<\/pee>\n<pee><strong>Inactivity<\/strong>:<\/pee>\n<pee><strong>Reverse<\/strong>: All benefits lost.<\/pee>\n<h3>Actions<\/h3>\n<pee><strong>Move<\/strong>:<\/pee>\n<pee><strong>Recommendation<\/strong>: 150 min\/week (moderate) or 75 min (intense).<\/pee>\n<pee><strong>Types<\/strong>:<\/pee>\n<ul class=\"styled-list\">\n<li>Brisk walking (30 min\/day).<\/li>\n<li>Swimming, cycling, dancing.<\/li>\n<li>Gardening, active housework.<\/li>\n<li>Strength training (2 times\/week).<\/li>\n<\/ul>\n<pee><strong>Lifelong<\/strong>:<\/pee>\n<pee><strong>Children<\/strong>: Daily activity (habits).<\/pee>\n<pee><strong>Adults<\/strong>: Maintain (stairs vs elevator).<\/pee>\n<pee><strong>Seniors<\/strong>: Adapt (gentle gym, water aerobics).<\/pee>\n<pee><strong>See dedicated article<\/strong>: Alzheimer&#8217;s&#8217;s and exercise (later).<\/pee>\n<pee><\/pee>\n<\/section>\n<div class=\"section-divider\">\u25c6 \u25c6 \u25c6<\/div>\n<section class=\"dynseo-section\">\n<h2 id=\"section-16\">Taking Action: Where to Start? {#agir}<\/h2>\n<h3>Assess Personal Risks<\/h3>\n<pee><strong>List of 12 Factors<\/strong>:<\/pee>\n<pee><strong>Check<\/strong>: Those that concern you.<\/pee>\n<pee><strong>Prioritize<\/strong>: Easily modifiable factors (quick wins).<\/pee>\n<h3>Progressive Action Plan<\/h3>\n<pee><strong>Not all at once<\/strong>:<\/pee>\n<pee><strong>Failure<\/strong>: Drastic changes (unsustainable).<\/pee>\n<pee><strong>Method<\/strong>: 1-2 factors \/ 3 months (anchor habits).<\/pee>\n<pee><strong>Examples<\/strong>:<\/pee>\n<pee><strong>Quarter 1<\/strong>: Quit smoking + Walk 30 min\/day.<\/pee>\n<pee><strong>Quarter 2<\/strong>: Control pressure + Reduce alcohol.<\/pee>\n<pee><strong>Quarter 3<\/strong>: Lose 5 kg + Join social club.<\/pee>\n<h3>Medical Follow-up<\/h3>\n<pee><strong>Assessment<\/strong>:<\/pee>\n<pee><strong>45 years<\/strong>: Hypertension, diabetes, cholesterol, BMI.<\/pee>\n<pee><strong>50 years<\/strong>: Audiogram.<\/pee>\n<pee><strong>60 years<\/strong>: Cognitive evaluation (baseline).<\/pee>\n<pee><strong>Regular<\/strong>: Primary care physician (adjust).<\/pee>\n<h3>Combine Factors<\/h3>\n<pee><strong>Synergy<\/strong>:<\/pee>\n<pee><strong>Exercise<\/strong>: Reduces obesity, diabetes, hypertension, depression, isolation.<\/pee>\n<pee><strong>Diet<\/strong>: Controls weight, diabetes, hypertension.<\/pee>\n<pee><strong>Social<\/strong>: Fights isolation, depression.<\/pee>\n<pee><strong>Act on multiple fronts<\/strong>: Maximizes benefits.<\/pee>\n<h3>Never Too Late<\/h3>\n<pee><strong>Even at 70<\/strong>:<\/pee>\n<pee><strong>Benefits<\/strong>: Exercise, social, diet (proven).<\/pee>\n<pee><strong>Decline<\/strong>: Slowed (improved quality of life).<\/pee>\n<pee><strong>Hope<\/strong>: Every change counts.<\/pee>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-17\">Testimonials<\/h2>\n<h3>John, 58 years old<\/h3>\n<pee><em>&#8220;45 years: Hypertension detected, ignored. 50 years: Overweight (BMI 32), smoker. Mother Alzheimer&#8217;s&#8217;s 72 years, fear. Read Lancet Commission. Decision: Act. Quit smoking (difficult, 6 months patches). Exercise: Cycling 3 times\/week. Diet: Less salt, more vegetables. 3 years later: BMI 26, normal pressure, fit. Fear Alzheimer&#8217;s&#8217;s? Still. But I act. Control.&#8221;<\/em><\/pee>\n<h3>Mary, 65 years old<\/h3>\n<pee><em>&#8220;Retirement: Isolation (friends gone, husband deceased). Latent depression. Daughter pushes to consult: Psychologist, antidepressants 6 months. Join book club, library volunteering. Now: Rich social life, better morale. Daughter says: &#8220;Mom transformed.&#8221; Alzheimer&#8217;s&#8217;s prevention? Didn&#8217;t think initially. Now understand: Act today = Protection tomorrow.&#8221;<\/em><\/pee>\n<h3>Paul, 72 years old<\/h3>\n<pee><em>&#8220;Believed too late (72 years). Son shows studies: &#8220;Never too late Dad.&#8221; Started daily walking (30 min), stopped excessive TV, cognitive activities (<a href=\"https:\/\/www.dynseo.com\/en\/brain-games-apps\/scarlett-brain-games-for-seniors\/\" target=\"_blank\">SCARLETT<\/a>, crosswords). 2 years later: Stable memory (cognitive tests), energy, optimism. Regretted not doing before, but proud now.&#8221;<\/em><\/pee>\n<pee><\/pee>\n<\/section>\n<section class=\"dynseo-section\">\n<h2 id=\"section-18\">Conclusion: 40% of Power in Your Hands<\/h2>\n<pee>Alzheimer&#8217;s&#8217;s \u2260 Inevitable fate. 40% preventable\/delayable cases = Revolution. 12 modifiable risk factors = 12 action levers. Education, hearing, smoking, depression, isolation, hypertension, obesity, diabetes, alcohol, trauma, pollution, inactivity: Each = Power. Act young (education, trauma prevention), midlife (hypertension, smoking, hearing), elderly (isolation, exercise): Lifelong = Opportunities. Lifestyle changes = Not guarantee (genetics, age remain), but maximize chances healthy brain. Start today. One factor. Then two. Then three. Your brain will thank you. Tomorrow, 10 years, 30 years. Alzheimer&#8217;s&#8217;s prevention = Marathon, not sprint. But every step counts.<\/pee>\n<pee><strong>The 12 factors to remember:<\/strong><\/pee>\n<pee>1. &#x2705; Education (maximize youth, compensate adult)<\/pee>\n<pee>2. &#x2705; Hearing (screen, use hearing aids)<\/pee>\n<pee>3. &#x2705; Smoking (quit)<\/pee>\n<pee>4. &#x2705; Depression (treat)<\/pee>\n<pee>5. &#x2705; Isolation (social connections)<\/pee>\n<pee>6. &#x2705; Hypertension (control)<\/pee>\n<pee>7. &#x2705; Obesity (lose weight)<\/pee>\n<pee>8. &#x2705; Diabetes (prevent, control)<\/pee>\n<pee>9. &#x2705; Alcohol (limit)<\/pee>\n<pee>10. &#x2705; Trauma (prevent)<\/pee>\n<pee>11. &#x2705; Pollution (reduce exposure)<\/pee>\n<pee>12. &#x2705; Inactivity (move)<\/pee>\n<pee><strong>You are not alone. Our <a href=\"https:\/\/www.dynseo.com\/en\/courses\/alzheimers-understanding-the-disease-and-finding-solutions-for-everyday-life\/\" target=\"_blank\">Alzheimer&#8217;s&#8217;s training<\/a> explains prevention. <a href=\"https:\/\/www.dynseo.com\/en\/brain-games-apps\/scarlett-brain-games-for-seniors\/\" target=\"_blank\">SCARLETT<\/a> stimulates cognition (cognitive reserve). <a href=\"https:\/\/www.dynseo.com\/en\/using-scarlett-to-help-people-suffering-from-alzheimers-disease\/\" target=\"_blank\">Free guide<\/a>: All resources.<\/strong><\/pee>\n<pee><\/pee>\n<pee><strong>DYNSEO resources for prevention:<\/strong><\/pee>\n<ul class=\"styled-list\">\n<li><a href=\"https:\/\/www.dynseo.com\/en\/courses\/alzheimers-understanding-the-disease-and-finding-solutions-for-everyday-life\/\" target=\"_blank\">Alzheimer&#8217;s&#8217;s Training: Understanding risk factors and prevention<\/a><\/li>\n<li><a href=\"https:\/\/www.dynseo.com\/en\/brain-games-apps\/scarlett-brain-games-for-seniors\/\" target=\"_blank\">SCARLETT: Daily cognitive stimulation (reserve)<\/a><\/li>\n<li><a href=\"https:\/\/www.dynseo.com\/en\/using-scarlett-to-help-people-suffering-from-alzheimers-disease\/\" target=\"_blank\">Free guide for supporting people with Alzheimer&#8217;s&#8217;s<\/a><\/li>\n<\/ul>\n<pee><\/pee>\n<pee><em>You read list 12 factors. Check mentally: Smoking (yes), sedentary (yes), isolation (starting). Fear rises. Then, realize: Power. Each factor = Lever. You decide: Quit smoking (now), walk 30 min daily (tomorrow), call lost friend (tonight). Small steps. But directed. Toward protected brain, long life, lucid. 40% in your hands. You clench fists. Act. Today.<\/em><\/pee><\/section>\n<\/div>\n<p>[\/et_pb_code][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243;][et_pb_row][et_pb_column type=&#8221;4_4&#8243;][et_pb_code]<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"What percentage of dementia cases could be prevented according to the WHO and Lancet Commission?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"According to the Lancet Commission (2020, updated 2024) and validated by the WHO, 40% of dementia cases could be prevented or delayed by acting on 12 modifiable risk factors. This represents a significant opportunity for prevention through lifestyle modifications.\"}},{\"@type\":\"Question\",\"name\":\"What are the 12 modifiable risk factors for Alzheimer's disease identified by the WHO?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"The 12 modifiable risk factors are: limited education, hearing loss, smoking, depression, social isolation, hypertension, obesity, diabetes, excessive alcohol consumption, head trauma, air pollution, and physical inactivity. These factors can be addressed at different life stages to reduce dementia risk.\"}},{\"@type\":\"Question\",\"name\":\"Is Alzheimer's disease purely genetic and unavoidable?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"No, this is false. While genetics play a role, Alzheimer's is not an inevitable genetic fate. Science reveals that lifestyle modifications can significantly impact risk, with 40% of cases being preventable through addressing modifiable risk factors, regardless of genetic predisposition.\"}},{\"@type\":\"Question\",\"name\":\"At what life stages do different Alzheimer's risk factors have the most impact?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Risk factors act at different life stages: some in youth (like limited education), others in midlife (such as hypertension, obesity, diabetes, smoking, and excessive alcohol), and others in elderly years (like social isolation and depression). Each stage offers opportunities for prevention.\"}},{\"@type\":\"Question\",\"name\":\"Is it too late to prevent Alzheimer's if you're already 60 years old?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"No, it's never too late. This is a common misconception. Modifying lifestyle factors at any age, including after 60, can still reduce Alzheimer's risk. Many risk factors like social isolation, physical inactivity, and managing health conditions can be addressed effectively in later life.\"}},{\"@type\":\"Question\",\"name\":\"Which risk factors for Alzheimer's affect people throughout their entire lifetime?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Three risk factors affect people lifelong: head trauma, air pollution, and physical inactivity. These factors can be managed and their impact reduced at any age through protective measures, environmental awareness, and maintaining an active lifestyle throughout life.\"}}]}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"What percentage of dementia cases could be prevented according to the WHO and Lancet Commission?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"According to the Lancet Commission (2020, updated 2024) and validated by the WHO, 40% of dementia cases could be prevented or delayed by acting on 12 modifiable risk factors. This represents a significant opportunity for prevention through lifestyle modifications.\"}},{\"@type\":\"Question\",\"name\":\"What are the 12 modifiable risk factors for Alzheimer's disease identified by the WHO?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"The 12 modifiable risk factors are: limited education, hearing loss, smoking, depression, social isolation, hypertension, obesity, diabetes, excessive alcohol consumption, head trauma, air pollution, and physical inactivity. These factors can be addressed at different life stages to reduce dementia risk.\"}},{\"@type\":\"Question\",\"name\":\"Is Alzheimer's disease purely genetic and unavoidable?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"No, this is false. While genetics play a role, Alzheimer's is not an inevitable genetic fate. Science reveals that lifestyle modifications can significantly impact risk, with 40% of cases being preventable through addressing modifiable risk factors, regardless of genetic predisposition.\"}},{\"@type\":\"Question\",\"name\":\"At what life stages do different Alzheimer's risk factors have the most impact?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Risk factors act at different life stages: some in youth (like limited education), others in midlife (such as hypertension, obesity, diabetes, smoking, and excessive alcohol), and others in elderly years (like social isolation and depression). Each stage offers opportunities for prevention.\"}},{\"@type\":\"Question\",\"name\":\"Is it too late to prevent Alzheimer's if you're already 60 years old?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"No, it's never too late. This is a common misconception. Modifying lifestyle factors at any age, including after 60, can still reduce Alzheimer's risk. Many risk factors like social isolation, physical inactivity, and managing health conditions can be addressed effectively in later life.\"}},{\"@type\":\"Question\",\"name\":\"Which risk factors for Alzheimer's affect people throughout their entire lifetime?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Three risk factors affect people lifelong: head trauma, air pollution, and physical inactivity. These factors can be managed and their impact reduced at any age through protective measures, environmental awareness, and maintaining an active lifestyle throughout life.\"}}]}<\/script>[\/et_pb_code][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p><div class=\"et_pb_row et_pb_row_0 et_pb_row_empty\">\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div> title: Alzheimer&#8217;s&#8217;s prevention: 12 modifiable risk factors WHO reduce dementia 40% description: Complete guide 12 modifiable risk factors Alzheimer&#8217;s&#8217;s according WHO Lancet: prevent 40% dementia cases, act on education, hearing, smoking, depression, social isolation, hypertension, obesity, diabetes, alcohol, head trauma, air pollution, physical inactivity and reduce disease risks. keywords: Alzheimer&#8217;s&#8217;s, prevention, risk factors, WHO, [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":323335,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[4545],"tags":[],"class_list":["post-438846","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-all-about-alzheimers"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Alzheimer&#039;s: The 12 Modifiable Risk Factors According to the WHO - DYNSEO - Educational apps &amp; brain training apps for all<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Alzheimer&#039;s: The 12 Modifiable Risk Factors According to the WHO - DYNSEO - Educational apps &amp; brain training apps for all\" \/>\n<meta property=\"og:description\" content=\"title: Alzheimer&#039;s&#039;s prevention: 12 modifiable risk factors WHO reduce dementia 40% description: Complete guide 12 modifiable risk factors Alzheimer&#039;s&#039;s according WHO Lancet: prevent 40% dementia cases, act on education, hearing, smoking, depression, social isolation, hypertension, obesity, diabetes, alcohol, head trauma, air pollution, physical inactivity and reduce disease risks. keywords: Alzheimer&#039;s&#039;s, prevention, risk factors, WHO, [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/\" \/>\n<meta property=\"og:site_name\" content=\"DYNSEO - Educational apps &amp; brain training apps for all\" \/>\n<meta property=\"article:published_time\" content=\"2025-12-11T10:28:36+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-12T01:04:02+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.dynseo.com\/wp-content\/uploads\/2023\/03\/seniors-with-dementia-alzheimer-association.png\" \/>\n\t<meta property=\"og:image:width\" content=\"500\" \/>\n\t<meta property=\"og:image:height\" content=\"500\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"DYNSEO\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"DYNSEO\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/\"},\"author\":{\"name\":\"DYNSEO\",\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/#\\\/schema\\\/person\\\/78ef63df2ee64e0989bc68f8401b38d6\"},\"headline\":\"Alzheimer&#8217;s: The 12 Modifiable Risk Factors According to the WHO\",\"datePublished\":\"2025-12-11T10:28:36+00:00\",\"dateModified\":\"2026-01-12T01:04:02+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/\"},\"wordCount\":1036,\"publisher\":{\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.dynseo.com\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/seniors-with-dementia-alzheimer-association.png\",\"articleSection\":[\"All About Alzheimer's\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/\",\"url\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/\",\"name\":\"Alzheimer's: The 12 Modifiable Risk Factors According to the WHO - DYNSEO - Educational apps &amp; brain training apps for all\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.dynseo.com\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/seniors-with-dementia-alzheimer-association.png\",\"datePublished\":\"2025-12-11T10:28:36+00:00\",\"dateModified\":\"2026-01-12T01:04:02+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.dynseo.com\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/seniors-with-dementia-alzheimer-association.png\",\"contentUrl\":\"https:\\\/\\\/www.dynseo.com\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/seniors-with-dementia-alzheimer-association.png\",\"width\":500,\"height\":500,\"caption\":\"Unlock the Power of Play: Educational Games for Children\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/alzheimers-12-modifiable-risk-factors-who\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Alzheimer&rsquo;s: The 12 Modifiable Risk Factors According to the WHO\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/\",\"name\":\"Jeux de m\u00e9moire et stimulation cognitive\",\"description\":\"DYNSEO, and your brain is a new hero!\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/#organization\",\"name\":\"DYNSEO\",\"url\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.dynseo.com\\\/wp-content\\\/uploads\\\/2022\\\/05\\\/logo-dynseo-new.png\",\"contentUrl\":\"https:\\\/\\\/www.dynseo.com\\\/wp-content\\\/uploads\\\/2022\\\/05\\\/logo-dynseo-new.png\",\"width\":5073,\"height\":1397,\"caption\":\"DYNSEO\"},\"image\":{\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/#\\\/schema\\\/person\\\/78ef63df2ee64e0989bc68f8401b38d6\",\"name\":\"DYNSEO\",\"url\":\"https:\\\/\\\/www.dynseo.com\\\/en\\\/author\\\/justine\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Alzheimer's: The 12 Modifiable Risk Factors According to the WHO - DYNSEO - Educational apps &amp; brain training apps for all","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/","og_locale":"en_US","og_type":"article","og_title":"Alzheimer's: The 12 Modifiable Risk Factors According to the WHO - DYNSEO - Educational apps &amp; brain training apps for all","og_description":"title: Alzheimer's's prevention: 12 modifiable risk factors WHO reduce dementia 40% description: Complete guide 12 modifiable risk factors Alzheimer's's according WHO Lancet: prevent 40% dementia cases, act on education, hearing, smoking, depression, social isolation, hypertension, obesity, diabetes, alcohol, head trauma, air pollution, physical inactivity and reduce disease risks. keywords: Alzheimer's's, prevention, risk factors, WHO, [&hellip;]","og_url":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/","og_site_name":"DYNSEO - Educational apps &amp; brain training apps for all","article_published_time":"2025-12-11T10:28:36+00:00","article_modified_time":"2026-01-12T01:04:02+00:00","og_image":[{"width":500,"height":500,"url":"https:\/\/www.dynseo.com\/wp-content\/uploads\/2023\/03\/seniors-with-dementia-alzheimer-association.png","type":"image\/png"}],"author":"DYNSEO","twitter_misc":{"Written by":"DYNSEO","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/#article","isPartOf":{"@id":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/"},"author":{"name":"DYNSEO","@id":"https:\/\/www.dynseo.com\/en\/#\/schema\/person\/78ef63df2ee64e0989bc68f8401b38d6"},"headline":"Alzheimer&#8217;s: The 12 Modifiable Risk Factors According to the WHO","datePublished":"2025-12-11T10:28:36+00:00","dateModified":"2026-01-12T01:04:02+00:00","mainEntityOfPage":{"@id":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/"},"wordCount":1036,"publisher":{"@id":"https:\/\/www.dynseo.com\/en\/#organization"},"image":{"@id":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/#primaryimage"},"thumbnailUrl":"https:\/\/www.dynseo.com\/wp-content\/uploads\/2023\/03\/seniors-with-dementia-alzheimer-association.png","articleSection":["All About Alzheimer's"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/","url":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/","name":"Alzheimer's: The 12 Modifiable Risk Factors According to the WHO - DYNSEO - Educational apps &amp; brain training apps for all","isPartOf":{"@id":"https:\/\/www.dynseo.com\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/#primaryimage"},"image":{"@id":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/#primaryimage"},"thumbnailUrl":"https:\/\/www.dynseo.com\/wp-content\/uploads\/2023\/03\/seniors-with-dementia-alzheimer-association.png","datePublished":"2025-12-11T10:28:36+00:00","dateModified":"2026-01-12T01:04:02+00:00","breadcrumb":{"@id":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/#primaryimage","url":"https:\/\/www.dynseo.com\/wp-content\/uploads\/2023\/03\/seniors-with-dementia-alzheimer-association.png","contentUrl":"https:\/\/www.dynseo.com\/wp-content\/uploads\/2023\/03\/seniors-with-dementia-alzheimer-association.png","width":500,"height":500,"caption":"Unlock the Power of Play: Educational Games for Children"},{"@type":"BreadcrumbList","@id":"https:\/\/www.dynseo.com\/en\/alzheimers-12-modifiable-risk-factors-who\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.dynseo.com\/en\/"},{"@type":"ListItem","position":2,"name":"Alzheimer&rsquo;s: The 12 Modifiable Risk Factors According to the WHO"}]},{"@type":"WebSite","@id":"https:\/\/www.dynseo.com\/en\/#website","url":"https:\/\/www.dynseo.com\/en\/","name":"Jeux de m\u00e9moire et stimulation cognitive","description":"DYNSEO, and your brain is a new hero!","publisher":{"@id":"https:\/\/www.dynseo.com\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.dynseo.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.dynseo.com\/en\/#organization","name":"DYNSEO","url":"https:\/\/www.dynseo.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.dynseo.com\/en\/#\/schema\/logo\/image\/","url":"https:\/\/www.dynseo.com\/wp-content\/uploads\/2022\/05\/logo-dynseo-new.png","contentUrl":"https:\/\/www.dynseo.com\/wp-content\/uploads\/2022\/05\/logo-dynseo-new.png","width":5073,"height":1397,"caption":"DYNSEO"},"image":{"@id":"https:\/\/www.dynseo.com\/en\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.dynseo.com\/en\/#\/schema\/person\/78ef63df2ee64e0989bc68f8401b38d6","name":"DYNSEO","url":"https:\/\/www.dynseo.com\/en\/author\/justine\/"}]}},"_links":{"self":[{"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/posts\/438846","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/comments?post=438846"}],"version-history":[{"count":6,"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/posts\/438846\/revisions"}],"predecessor-version":[{"id":479846,"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/posts\/438846\/revisions\/479846"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/media\/323335"}],"wp:attachment":[{"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/media?parent=438846"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/categories?post=438846"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.dynseo.com\/en\/wp-json\/wp\/v2\/tags?post=438846"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}